Mary Butler, PhD, MBA

Associate Professor, Division of Health Policy and Management

Mary Butler

Contact Info

Office Phone 612-624-6124

Office Address:
D381 Mayo

Mailing Address:
420 Delaware St SE
MMC 729 Mayo
Minneapolis, MN 55455

Associate Professor, Division of Health Policy and Management

Co-Director, Minnesota Evidence-based Practice Center, School of Public Health

Graduate Faculty, Center on Aging, Gerontology Minor, School of Public Health

PhD, Health Services Research, Policy and Administration, University of Minnesota, 2007

MBA, Investment Finance, University of Minnesota, 1991

BS, Economics/Finance/Computer Science, University of Minnesota, 1987

NECSI Certificate: Complex Physical, Biological, and Social Systems, June 2012

NECSI Certificate: Complex Systems Modeling and Networks, Jan. 2013


I study scientific evidence standards, research design and systematic review methodology, evidence-informed health care, and complex patients and complex interventions. As Co-Director of the Minnesota Evidence-based Practice Center, I oversee AHRQ review programs on a wide range of topics, specializing in complex patients and complex interventions.

Prior to joining SPH, I worked as an investment professional for a financial services firm. I managed a $45 million portfolio, managed multiple teams to meet financial and investment objectives, and created portfolio benchmarks to track performance


Health services research, outcomes research, health behaviors in alternative health


Research Summary/Interests

Minnesota Evidence-based Practice projects:

  • Values of Older Adults related to Primary and Secondary Prevention,
  • Treatment of Common Hip Fractures,
  • Treatments for Bipolar Disorder,
  • Early Diagnosis, Prevention, and Treatment of C. Difficile Infection
  • Quality Improvement Outcome Measurement for People with Disabilities,
  • Decisional Dilemmas in Discontinuing Prolonged Disease-Modifying Treatment for Multiple Sclerosis
  • Interventions to Improve Cultural Competence
  • Interventions to Prevent Age-Related Cognitive Decline, MCI, and Clinical Alzheimer’s-Type Dementia

Research Funding Grants

  • 2015–2017, University of Pennsylvania, "University of Pennsylvania+ PLUS Clinical Center (PENN+PLUS CC)," Co-Investigator
  • 2014–2019, US Dept of Health & Human Services AHRQ, "Evidence-Based Practice Centers (EPC)," Co-Investigator


Selected Publications

  • Kane RL, Butler M, Ng W. "Examining the quality of evidence to support the effectiveness of interventions: an analysis of systematic reviews," BMJ Open, May 2016
  • Butler M, McCreedy E, Schwer N, Burgess D, Call K, Przedworski J, Rosser S, Larson S, Allen M, Fu S, Kane RL. "Improving Cultural Competence to Reduce Health Disparities," Comparative Effectiveness Reviews, March 2016
  • Jutkowitz E, Brasure M, Fuchs E, Shippee T, Kane RA, Fink HA, Butler M, Sylvanus T, Kane RL. "Care-Delivery Interventions to Manage Agitation and Aggression in Dementia Nursing Home and Assisted Living Residents: A Systematic Review and Meta-analysis," Journal of the American Geriatrics Society, March 2016
  • Wysocki A, Butler M, Kane RL, Kane RA, Shippee T, Sainfort F. "Long-Term Services and Supports for Older Adults: A Review of Home and Community-Based Services Versus Institutional Care," Journal of Aging & Social Policy, May 2015



  • PubH 6803, Conducting a Systematic Literature Review


In The News

SPH News

In The Media

  • No 'magic bullet' for preventing cognitive decline, study suggests (Pharmacy Today)