Pamela Lutsey, PhD, MPH

Professor, Division of Epidemiology and Community Health

Pamela Lutsey

Contact Info

Office Phone 612-624-5812

Office Address:
451 West Bank Office Building

Mailing Address:
1300 S 2nd St
300 West Bank Office Building
Minneapolis, MN 55454

PhD, Epidemiology, University of Minnesota

MPH, Epidemiology, University of Minnesota

BS, Community Health Education, Iowa State University

BA, Psychology, Iowa State University


Pamela Lutsey is an epidemiologist whose mission is to identify potentially changeable factors that influence risk of cardiovascular disease (CVD) and other chronic conditions. Areas of particular interest include nutritional biomarkers (e.g. serum magnesium), sleep disordered breathing, venous thromboembolism, and the identification of risk factors for dementia. Much of Dr. Lutsey’s research calls on two long term studies: The Atherosclerosis Risk in Communities (ARIC) Study and the Multi-Ethnic Study of Atherosclerosis (MESA). She is also using large administrative data sources (i.e. MarketScan, Medicare) to compare the effectiveness of new versus established treatment strategies for venous thromboembolism and atrial fibrillation.


Aging, chronic diseases, equity, cardiovascular disease, sleep, pharamcoepidemiology, dementia

Awards & Recognition

  • Fellow of the American Heart Association, conferred by the Council on Epidemiology and Prevention (2017)
  • McKnight Land-Grant Professor (2014–2016)
  • American Heart Association Early Career Committee (2012–2014)
  • Multi-Ethnic Study of Atherosclerosis Young Investigator Award (2012)


Research Funding Grants

  • 2017–2021, NIH NHLBI, "Epidemiology of Venous Thrombosis and Pulmonary Embolism (LITE)," Co-Investigator
  • 2017–2022, NIH NHLBI, "Contemporary Venous Thromboembolism Treatment," Principal Investigator
  • 2019–2023, NIH NHLBI, "ARIC Neurocognitive Study (ARIC-NCS) Renewal," Subcontract Principal Investigator
  • 2019–2024, NIH NHLBI, "Multi-Ethnic Study of Atherosclerosis (MESA)," Co-Investigator
  • 2021–2026, NIH NHLBI, "Mentoring and Research in Patient-Oriented Cardiovascular Pharmacoepidemiology," Principal Investigator
  • 2022–2028, NIH NHLBI, "Atherosclerosis Risk in Communities Study," Principal Investigator


See a full list of my publications on PubMed

Select Recent Publications

  • Lutsey PL, Norby FL, Ensrud KE, MacLehose RF, Diem SJ, Chen LY, Alonso A. Association of anticoagulant therapy with risk of fracture among patients with atrial fibrillation. JAMA Internal Medicine. 2020;180(2):245-253.
  • +Walker RF, Zakai NA, MacLehose RF, Cowan LT, Adam TJ, Alonso A, Lutsey PL. Association of testosterone therapy with risk of venous thromboembolism among men with and without hypogonadism. JAMA Internal Medicine 2020;180(2):190-197.
  • Fanola CL, Norby FL, Shah AM, Chang PP, Lutsey PL, Rosamond WD, Cushman M, Folsom AR. Incident heart failure and long-term risk for venous thromboembolism. Journal of the American College of Cardiology 2020;75(2):148-158.
  • +Full KM, Jackson CL, Rebholz CM, Matsushita K, Lutsey PL. Obstructive sleep apnea, other sleep characteristics, and risk of CKD in the Atherosclerosis Risk in Communities Sleep Heart Health Study. Journal of the American Society of Nephrology 2020;31(8):1859-1869.
  • +Rooney MR, Alonso A, Folsom AR, Michos ED, Rebholz CM, Misialek JR, Chen LY, Dudley S, Lutsey PL. Serum magnesium and the incidence of coronary artery disease over a median 27 years of follow-up in the Atherosclerosis Risk in Communities (ARIC) Study and a meta-analysis. American Journal of Clinical Nutrition 2020;111(1):52-60.
  • Lutsey PL, Chen N, Mirabelli MC, Lakshminarayan K, Knopman DS, Vossel KA, Gottesman RF, Mosley TH Alonso A. Impaired lung function, lung disease, and risk of incident dementia. American Journal of Respiratory and Critical Care Medicine 2019;199(11):1385-1396. PMCID: PMC6543713
  • Lutsey PL, Walker RF, MacLehose RF, Alonso A, Adam TJ, Zakai NA. Direct oral anticoagulants and warfarin for venous thromboembolism treatment: Trends from 2012 to 2017. Research and Practice in Thrombosis and Haemostasis 2019;3(4):668-673. PMCID: PMC6782014
  • Lutsey PL, Zakai NA, MacLehose RF, Norby FL, Walker RF, Roetker NS, Adam TJ, Alonso A. Risk of hospitalised bleeding in comparisons of oral anticoagulant options for the primary treatment of venous thromboembolism. British Journal of Haematology 2019;185(5):903-911. PMCID: PMC6536346
  • +Olgilvie RP, MacLehose RF, Alonso A, Norby FL, Lakshminarayan K, Iber C, Chen LY, Lutsey PL. Diagnosed sleep apnea and cardiovascular disease in atrial fibrillation patients: The role of measurement error from administrative data. Epidemiology 2019;30(6):885-892. PMCID:
  • Walker KA, Sharrett AR, Wu A, Schneider ALC, Albert M, Lutsey PL, Bandeen-Roche K, Coresh J, Gross AL, Windham BG, Knopman DS, Power MC, Rawlings AM, Mosley TH, Gottesman RF. Association of midlife to late-life blood pressure patterns with incident dementia. JAMA 2019;322(6):535-545. PMCID: PMC6692677
  • Wang SY, Tan ASL, Claggett B, Chandra A, Khatana SAM, Lutsey PL, Kucharska-Newton A, Koton S, Solomon SD, Kawachi I. Longitudinal associations between income changes and incident cardiovascular disease: The Atherosclerosis Risk in Communities Study. JAMA Cardiol 2019;4(12):1203-1212. PMCID: PMC6802267
  • Lutsey PL, Misialek JR, Mosley TH, Gottesman RF, Punjabi NM, Shahar E, MacLehose R, Olgilvie RP, Knopman D, Alonso A. Sleep characteristics and risk of dementia and Alzheimer's disease: The Atherosclerosis Risk in Communities Study. Alzheimers Dement 2018;14(2):157-166. PMCID: PMC5776061
  • +Whitaker KM, Lutsey PL, Olgilvie RP, Pankow JS, Bertoni A, Michos ED, Punjabi N, Redline S. Associations between polysomnography and actigraphy-based sleep indices and glycemic control among those with and without type 2 diabetes: The Multi-Ethnic Study of Atherosclerosis. Sleep 2018;41(11):zsy712. PMCID: PMC6231520
  • +Rooney MR, Harnack L, Michos ED, Olgilvie RP, Sempos CT, Lutsey PL. Trends in use of high-dose vitamin D supplements exceeding 1000 or 4000 international units daily, 1999-2014. JAMA 2017;317(23):2448-2450. PMCID: PMC5587346
  • +Whitaker KM, Everson-Rose SA, Pankow JS, Rodriguez CJ, Lewis TT, Kershaw KN, Diez Roux AV, Lutsey PL. Experiences of discrimination and incident type 2 diabetes mellitus: The Multi-Ethnic Study of Atherosclerosis (MESA). American Journal of Epidemiology 2017;186(4):445-455. PMCID: PMC5860562
  • Lutsey PL, Bengtson LG, Punjabi NM, Shahar E, Mosley TH, Gottesman RF, Wruck LM, MacLehose RF, Alonso A. "Obstructive sleep apnea and 15-year cognitive decline: The Atherosclerosis Risk in Communities (ARIC) Study," Sleep 2016;39(2):309-316. PMCID: PMC4712410
  • Hoofnagle AN, Eckfeldt JH, Lutsey PL. "Vitamin D-binding protein concentrations quantified by mass spectrometry" [Letter to the Editor]. New England Journal of Medicine 2015;373(15)1480-1482. PMCID: PMC4654614
  • Lutsey PL, Michos ED, Misialek JR, Pankow JS, Loehr L, Selvin E, Reis JP, Gross M, Eckfeldt JH, Folsom AR. Race and vitamin D binding protein gene polymorphisms modify the association of 25-hydroxyvitamin D and incident heart failure: The ARIC (Atherosclerosis Risk in Communities) Study. Journal of the American College of Cardiology. Heart Failure 2015;3(5):347-356. PMCID: PMC4426050.
  • Lutsey PL, McClelland RL, Duprez D, Shea S, Shahar E, Nagayoshi M, Budoff M, Kaufman JD, Redline S. "Objectively measured sleep characteristics and prevalence of coronary artery calcification: the Multi-Ethnic Study of Atherosclerosis Sleep study," Thorax 2015;70(9):880-887. PMCID: PMC4858321
  • Lutsey PL, Alonso A, Selvin E, Pankow JS, Michos ED, Agarwal SK, Loehr LR, Eckfeldt JH, Coresh J. "Fibroblast growth factor-23 and incident coronary heart disease, heart failure, and cardiovascular mortality: the Atherosclerosis Risk in Communities study," Journal of the American Heart Association 2014;3(3):e000936. PMCID: PMC4309096


Teaching Areas

I take an active role in training future public health professionals an have mentored and advised graduate students within the Epidemiology & Community Health Division. I am a primary faculty member on the the T32 training grant in Cardiovascular Disease Epidemiology and Prevention.



In The News

SPH News

  • New Anti-Blood Clot Drugs Appear Safe for Cancer Patients (Read More)
  • Lung Disease in Middle Age May Be a Risk Factor for Dementia Later in Life (Read More)
  • Understanding Patient Drug Preferences for Treating Venous Thromboembolism (Read More)
  • Study Confirms Link Between Height and Venous Thromboembolism (Read More)
  • Use of High-Dose Vitamin D Supplements Increasing Among Americans (Read More)
  • Study Links Six Biomarkers to Deadly Aortic Aneurysms (Read More)
  • Conquering Heart Disease for 30 Years (Read More)
  • Study Links High Blood Calcium with Diabetes (Read More)
  • UMN Study Raises Questions About the Best Way to Assess Vitamin D Status (Read More)

In The Media

  • Many in U.S. Take More Calcium Supplements than Necessary (KFGO)