Jeffrey Mandel, MD, MPH

Professor Emeritus, Division of Environmental Health Sciences

Jeffrey Mandel

Contact Info

Office Phone 612-626-9308

Office Address:
1240 Mayo

Mailing Address:
420 Delaware St SE
MMC 807 Mayo
Minneapolis, MN 55455

MD, Medicine, Loyola University School of Medicine, 1975

MPH, Epidemiology, University of Minnesota, 1985

BS, University of North Dakota, 1971


A key area of research of mine is the exposure-disease relationship, particularly exposures that involve dust and particulates. I have been involved in research that has explored traditional and non-traditional exposure metrics and exposures directly measured in the body. This work has included the assessment of a variety of compounds and health effects, including organic solvents, metals, respirable dust, silica, asbestiform and non-asbestiform elongate mineral particles, fluoroalkyl compounds and others. This work has been multidisciplinary in scope and has involved the fields of medicine, radiology, toxicology, biostatistics, epidemiology and exposure science. Over the past six years, I have been PI for a multi-disciplinary evaluation of exposures and related health issues in the taconite mining industry of Minnesota.


Chronic diseases, environment and exposures, exposures, epidemiology, pulmonary, cancer, pneumoconiosis, occupational health

Awards & Recognition

  • Member, Delta Omega Honorary Society in Public Health


Research Funding Grants

  • 2016–2017, CDC Nat'l Inst for Occup Safety & Health, "Midwest Center for Occupational Health & Safety Training Grant," Co-Investigator
  • 2014–2017, NIOSH, "Use of Personal Monitoring Data in Epidemiologic Assessments of Taconite Workers," Co-Investigator
  • 2014–2017, "Environmental Associations in Parkinson's Disease in Minnesota," Co-Investigator


See a full list of publications on PubMed

Select Recent Publications

  • Mandel JH, Alexander BH, Ramachandran G. "A review of mortality associated with elongate mineral particle (EMP) exposure in occupational epidemiology studies of gold, talc, and taconite mining," American Journal of Industrial Medicine, Oct 2016
  • Mandel JH, Ramachandran G, Alexander BH. "Increased Lung Cancer Mortality in Taconite Mining: The Potential for Disease from Elongate Mineral Particle Exposure," Chemical Research in Toxicology, Jan 2016
  • Lambert CS, Alexander BH, Ramachandran G, MacLehose RF, Nelson HH, Ryan AD, Mandel JH. "A case-control study of mesothelioma in Minnesota iron ore (taconite) miners.," Occupational & Environmental Medicine, Feb 2016
  • Allen EM, Alexander BH, MacLehose RF, Nelson HH, Ramachandran G, Mandel JH. "Cancer incidence among Minnesota taconite mining industry workers," Annals of Epidemiology, Nov 2015
  • Mandel JH, Wendt C, Lo C, Zhou G, Hertz M, Ramachandran G."Ambient air pollution and lung disease in China: health effects, study design approaches and future research," Frontiers of Medicine, Sept 2015



  • PubH 6130, Occupational Medicine: Principles and Practice



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