Chap Le, PhD

Distinguished Professor, Division of Biostatistics

Chap Le

Contact Info

Office Phone 612-624-9963

Office Address:
A441 Mayo

Mailing Address:
420 Delaware St SE
MMC 303 Mayo
Minneapolis, MN 55455

Distinguished Professor, Division of Biostatistics

Director of Biostatistics, Masonic Cancer Center (MCC)

PhD, Statistics, University of New Mexico

MA, Mathematics, California State University-Fresno

BA, Mathematics, California State University-Fresno

BS, Mechanical Engineering, California State University-Fresno


My research interests are data-driven and include epidemiological methods, cross-over designs, survival analysis, ordered alternatives, ROC curves, and methods for the analysis of In Vitro experiments. My research collaborations focus on the analyses of survival and categorical data, specifically in the areas of cancer and tobacco research. 


Chronic diseases, environment & exposures, tobacco, smoking, cessation, health care policy, global health

Awards & Recognition

  • Member, Delta Omega Honorary Society in Public Health


Research Funding Grants

  • 2017-2022, NIH (P01), “Consortium on Methods Evaluating Tobacco (COMET): Filter Ventilation and Product Standards”, Director of Biostatistics and Data Management Core.
  • 2017-2022, FDA/Wake Forest University (U54), “Evaluating New Nicotine Standards for Cigarettes”, Director of Biostatistics Core.
  • 2016–2021, NIH/NCI (P01), "NK Cells, Their Receptors, Transplantation and Cancer Therapy," Director of Biostatistics Core
  • 2015–2020, NIH/NCI (P01), "Biology and Transplantation of the Hematopoietic Stem Cell," Director of Biostatistics Core
  • 2014–2019, NIH (R01), "Nornicotine in smokeless tobacco as a precursor for carcinogen exposure," Co-Investigator
  • 2014–2019, NIH (R01), "Metabolism of Carcinogenic Tobacco-Specific Nitrosamines," Co-Investigator
  • 2014–2019, NIH/NCI (P30), "Cancer Center Support Grant," Director of Biostatistics Shared Resource
  • 2016-2018, FDA (U19, NCE), "Models for Tobacco Products Evaluation", Director of Biostatistics Core
  • 2013–2018, NIH/NIMHD (U54), "National Transdisciplinary Collaborative Center for African American Men's Health," Co-Investigator/Statistician


See a full list of publications on Google Scholar


  • Introductory Biostatistics, Second Edition (Co-author: Lyn Eberly); John Wiley and Sons, 2016
  • Applied Categorical Data Analysis and Translational Research; John Wiley and Sons, 2009
  • Health and Numbers: Introductory Biostatistics with Microsoft Excel; John Wiley and Sons, 2009
  • Statistics Quick Reference Guide for Medical Affair (For training at AstraZeneca), 2007
  • Introductory Biostatistics; John Wiley and Sons, 2003
  • Health and Numbers: A Problems-Based Introduction to Biostatistics; John Wiley and Sons, 2001
  • Applied Categorical Data Analysis; John Wiley and Sons, 1998
  • Applied Survival Analysis; John Wiley and Sons, 1997
  • Health and Numbers: Basic Biostatistical Methods; John Wiley and Sons, 1995 (Co-author J.B. Boen)
  • Fundamentals of Biostatistical Inference; Marcel Dekker, Inc., 1992